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17 278 (0,135s)

Result

Lewis Base-Catalyzed Enantioselective Allylation of alpha,beta-Unsaturated Aldehydes.

Catalytic allylation of alpha,beta-unsaturated aldehydes with allyltrichlorosilane in the presence of chiral 3,3'-unsymmetrically substituted bis(tetra-hydroisoquinoline) N,N-dioxides was explored....

CC - Organická chemie

  • 2010
  • Jx
Result

Highly Enantioselective Aza-Baylis-Hillman-Type Reaction of alpha,beta-Unsaturated Aldehydes with In Situ Generated N-Boc- and N-Cbz-Imines

An organocatalytic highly enantioselective aza-Baylis-Hillman reaction of alpha,beta-unsaturated aldehydes with in situ generated N-Boc- and N-Cbz-imines is presented. This novel process opens the pathway for the synthesis ...

CC - Organická chemie

  • 2009
  • Jx
Result

1,4-Addition of tetraethyl fluoromethylenebisphosphonate to alpha, beta-unsaturated compounds

Tetraethyl fluoromethylenebisphosphonate in the presence of cesium carbonate in DMF undergoes efficient 1,4-addition to Michael acceptors having terminal double bond such as alpha,beta-unsaturated ketones, esters, sulfones,...

CC - Organická chemie

  • 2011
  • Jx
  • Link
Result

Conjugate addition of diethyl 1-fluoro-1-phenylsulfonylmethanephosphonate to alpha,beta-unsaturated compounds

Diethyl 1-fluoro-1-phenylsulfonylmethanephosphate (1) in the presence of cesium carbonate undergoes efficient 1,4-addition to Michael acceptors having terminal double bonds such as alpha,beta-unsaturated ketones, esters, su...

CC - Organická chemie

  • 2013
  • Jx
  • Link
Result

Asymmetric Aza-Morita-Baylis-Hillman-type reactions: The highly enantioselective reaction between unmodified alpha,beta-unsaturated aldehydes and N-acyl imines by organo-co-catalysis

The organo-co-catalytic aza-Morita-Baylis-Hillman (MBH)-type reaction between N-carbamate protected imines and alpha,beta-unsaturated aldehydes has been developed. The organic co-catalytic system of proline and DABCO enable...

CC - Organická chemie

  • 2011
  • Jx
  • Link
Result

Diastereoselective Cyclopropanation through Michael Addition-Initiated Ring Closure between alpha,alpha-Dibromoketones and alpha,beta-Unsaturated Fischer Carbene Complexes

The diastereoselective synthesis of tetrasubstituted cyclopropanes is described. The two-step procedure is based on the 3-exo-tet Michael addition-initiated ring closure. In the first step, the enolates derived from alpha,alpha-dibr...

Organic chemistry

  • 2020
  • Jimp
  • Link
Result

Polyfunctional beta-Dicarbonyl Compounds by Michael Addition Reactions of Ester Enolates to alpha-Benzylidene and alpha-Alkylidene-beta-dicarbonyl Compounds

to a-benzylidene and a-alkylidene beta-dicarbonyl compounds was studied. Most substrates functionalities reacted directly in the beta-position, whereas aldol and Michael addition competed with unsaturated ketones. The dias...

CC - Organická chemie

  • 2012
  • Jx
  • Link
Result

Highly Enantioselective Addition of 1-Fluoro-1-nitro(phenylsulfonyl)methane to alpha,beta-Unsaturated Aldehydes

An organocatalytic, highly enantioselective addition of 1- fluoro-1-nitro(phenylsulfonyl)methane to alfa,beta-unsaturated aldehydes is reported. The reaction is simply catalyzed by secondary amines and furnishes the corresponding fl...

CC - Organická chemie

  • 2010
  • Jx
Result

Highly enantioselective organocatalytic alpha-selenylation of aldehydes using hypervalent iodine compounds

for the preparation of biologically active building blocks such as beta-hydroxy alcohols, alpha-amino acids, and alpha-hydroxy esters.The highly enantioselective organocatalytic alpha-selenylation reaction. This t...

CC - Organická chemie

  • 2013
  • Jx
  • Link
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