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Hematopoietic Stem Cells Survive Circulation Arrest and Reconstitute Hematopoiesis in Myeloablated Mice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10108941" target="_blank" >RIV/00216208:11310/11:10108941 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/11:8875

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bbmt.2011.07.007" target="_blank" >http://dx.doi.org/10.1016/j.bbmt.2011.07.007</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bbmt.2011.07.007" target="_blank" >10.1016/j.bbmt.2011.07.007</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Hematopoietic Stem Cells Survive Circulation Arrest and Reconstitute Hematopoiesis in Myeloablated Mice

  • Original language description

    Hematopoietic stem and progenitor cells (HSPC) for bone marrow transplantation are currently obtained directly from living voluntary donors or from cord blood units. However, a suitable donor is not always found. Because HSPC are known for their relativeresistance to hypoxia, using an experimental murine model, we explored cadaveric bone marrow (BM) as their alternative source. This paper shows that HSPC survive the cessation of circulation for a considerable time and maintain their engraftment potential. This time is significantly extended with in vitro storage compared to the cadaveric BM.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LC06044" target="_blank" >LC06044: Center for Experimental Hematology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biology of Blood and Marrow Transplantation

  • ISSN

    1083-8791

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    1273-1281

  • UT code for WoS article

    000294594900002

  • EID of the result in the Scopus database