Comparison of LC Columns Packed with 2.6 mu m Core-Shell and Sub-2 mu m Porous Particles for Gradient Separation of Antibiotics

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10112536" target="_blank" >RIV/00216208:11310/11:10112536 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s10337-011-2021-7" target="_blank" >http://dx.doi.org/10.1007/s10337-011-2021-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10337-011-2021-7" target="_blank" >10.1007/s10337-011-2021-7</a>

Result language

angličtina

Original language name

Comparison of LC Columns Packed with 2.6 mu m Core-Shell and Sub-2 mu m Porous Particles for Gradient Separation of Antibiotics

Original language description

The recently introduced Kinetex C18 column packed with core-shell 2.6 mu m particles is declared to provide similar efficiency and short analysis as Acquity BEH C18 column with 1.7 mu m porous particles. Unlike Acquity BEH C18 column, Kinetex C18 columnexhibited lower column backpressure making this column compatible to conventional LC systems. The performance of Kinetex C18 column (2.1 x 50 mm) and Acquity BEH C18 column (2.1 x 50 mm) for gradient separation of tetracyclines under acidic conditions (oxytetracycline, tetracycline, chlortetracycline, and doxycycline) and macrolides under alkaline conditions (tylosin, clarithromycin, roxithromycin, and carbomycin) was studied. The columns were compared by evaluation of their experimental peak capacity and its dependence on linear velocity and gradient slope. The maximal experimental peak capacities for analysis of tetracyclines were 51.8 (Acquity BEH C18 column) and 48.4 (Kinetex C18 column). This indicated that Kinetex C18 was a suitab

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/1M06011" target="_blank" >1M06011: The Centre of Molecular Methods for Monitoring the Diffuse Pollution of the Environment.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chromatographia

ISSN

0009-5893

e-ISSN

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Volume of the periodical

74

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

19-27

UT code for WoS article

000291745400003

EID of the result in the Scopus database

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