Chemical cross-linking and H/D exchange for fast refinement of protein crystal structure

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10104144" target="_blank" >RIV/00216208:11310/12:10104144 - isvavai.cz</a>
Alternative codes found
RIV/86652036:_____/12:00389121 RIV/61388971:_____/12:00389121
Result on the web
<a href="http://dx.doi.org/10.1021/ac202818m" target="_blank" >http://dx.doi.org/10.1021/ac202818m</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/ac202818m" target="_blank" >10.1021/ac202818m</a>

Result language
angličtina
Original language name
Chemical cross-linking and H/D exchange for fast refinement of protein crystal structure
Original language description
Combination of chemical cross-linking and hydrogen- deuterium exchange coupled to high resolution mass spectrometry was used to describe structural differences of NKR-P1A receptor. The loop region extended from the compact core in the crystal structure was found to be closely attached to the protein core in solution. Our approach has potential to refine protein structures in solution within few days and has very low sample consumption.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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