Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10123865" target="_blank" >RIV/00216208:11310/12:10123865 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/12:00377347
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats
Original language description
We have studied the effect of sustained administration of morphine in high doses on myocardial adenylyl cyclase signaling and cardiac ischemic tolerance. Our results indicated that prolonged treatment of morphine substantially alters the function of myocardial G-protein-regulated adenylyl cyclase signaling and reduced susceptibility to ischemia-induced ventricular arrhythmias.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/IAA501110901" target="_blank" >IAA501110901: Molecular mechanisms of adverse and protective effects of morphine and methadone on the rat heart</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pharmacological Reports
ISSN
1734-1140
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
2
Country of publishing house
PL - POLAND
Number of pages
9
Pages from-to
351-359
UT code for WoS article
000305546700014
EID of the result in the Scopus database
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