Synthesis of 2 '-deoxy-2 '-fluororibo- and 2 '-deoxy-2 ',2 '-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10126889" target="_blank" >RIV/00216208:11310/12:10126889 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/12:00382176
Result on the web
<a href="http://dx.doi.org/10.1016/j.tet.2012.07.033" target="_blank" >http://dx.doi.org/10.1016/j.tet.2012.07.033</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tet.2012.07.033" target="_blank" >10.1016/j.tet.2012.07.033</a>

Result language
angličtina
Original language name
Synthesis of 2 '-deoxy-2 '-fluororibo- and 2 '-deoxy-2 ',2 '-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines
Original language description
A series of novel sugar-modified derivatives of cytostatic 6-hetaryl-7-deazapurine ribonucleosides (2'-deoxy-2'-fluororibo- and 2'-deoxy-2',2-difluororibonucleosides) bearing an aryl or hetaryl group in position 6, was prepared and screened for biological activity. The title nucleosides did not show considerable cytostatic or antiviral activity.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
<a href="/en/project/GAP207%2F11%2F0344" target="_blank" >GAP207/11/0344: Combinatorial and rational approaches for the synthesis and evaluation of novel modified nucleosides with cytostatic and antimicrobial activity</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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