Synthesis of 3(I)-O and 2(I)-O-monosubstituted derivatives of per-6-azido-beta-cyclodextrin-potential molecular scaffolds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10126925" target="_blank" >RIV/00216208:11310/12:10126925 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.carres.2012.09.003" target="_blank" >http://dx.doi.org/10.1016/j.carres.2012.09.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carres.2012.09.003" target="_blank" >10.1016/j.carres.2012.09.003</a>
Alternative languages
Result language
angličtina
Original language name
Synthesis of 3(I)-O and 2(I)-O-monosubstituted derivatives of per-6-azido-beta-cyclodextrin-potential molecular scaffolds
Original language description
Alkylation of per-6-azido-beta-cyclodextrin by a suitable electrophilic reagent (cinnamyl bromide or propargyl bromide) gave a mixture of 3(I)-O and 2(I)-O regioisomers. After peracetylation and chromatographic separation on silica gel, pure isomers wereisolated. Oxidative cleavage of cinnamyl double bond afforded the corresponding formylmethyl and carboxymethyl derivatives. The prepared scaffold molecules are equipped with two types of reactive groups which have a potential to serve as points of attachment for various compounds.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Carbohydrate Research
ISSN
0008-6215
e-ISSN
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Volume of the periodical
361
Issue of the periodical within the volume
November
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
148-154
UT code for WoS article
000310843700021
EID of the result in the Scopus database
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