Enantioselective separation of unusual amino acids by high performance liquid chromatography

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10139881" target="_blank" >RIV/00216208:11310/13:10139881 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.seppur.2013.09.010" target="_blank" >http://dx.doi.org/10.1016/j.seppur.2013.09.010</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.seppur.2013.09.010" target="_blank" >10.1016/j.seppur.2013.09.010</a>

Result language

angličtina

Original language name

Enantioselective separation of unusual amino acids by high performance liquid chromatography

Original language description

Unusual amino acids, i.e. amino acids not encoded by DNA, play fundamental roles in many scientific fields. Since the single enantiomeric form can cause different and often serious response of organisms, chiral separations of unusual amino acids are irreplaceable tools in their study and their employment. Two types of chiral stationary phases, two teicoplanin-based and four polysaccharidebased columns, were used. Separation conditions of reversed phase mode, polar organic mode and hydrophilic interaction chromatography were evaluated and compared. All columns used exhibited significantly different enantioselectivities. Teicoplanin-based chiral stationary phases, especially Chirobiotic T column, were able to separate almost all enantiomers tested, withthe exception of Z-D,L- 4-F-phenylalanine ethyl ester. No partial enantioseparation of this analyte was obtained on teicoplanin- based chiral stationary phases, while baseline enantioresolution was achieved on polysaccharide- based column

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

<a href="/en/project/LH11018" target="_blank" >LH11018: Cyclofructans and their derivatives as new chiral selectors for liquid chromatography and capillary electrophoresis</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Separation and Purification Technology

ISSN

1383-5866

e-ISSN

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Volume of the periodical

119

Issue of the periodical within the volume

November

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

123-128

UT code for WoS article

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EID of the result in the Scopus database

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