Mesenchymal Stem Cells, Nanofiber Scaffolds and Ocular Surface Reconstruction

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10189226" target="_blank" >RIV/00216208:11310/13:10189226 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/13:00396248
Result on the web
<a href="http://dx.doi.org/10.1007/s12015-013-9449-0" target="_blank" >http://dx.doi.org/10.1007/s12015-013-9449-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12015-013-9449-0" target="_blank" >10.1007/s12015-013-9449-0</a>

Result language
angličtina
Original language name
Mesenchymal Stem Cells, Nanofiber Scaffolds and Ocular Surface Reconstruction
Original language description
Ocular surface defects represent one of the most common causes of impaired vision or even blindness. For treatment, keratoplasty represents the first choice. However, if corneal defects are more extensive and associated with a limbal stem cell (LSC) deficiency, corneal transplantation is not a sufficient therapeutic procedure and only viable approach to treatment is the transplantation of LSCs. When the LSC deficiency is a bilateral disorder, autologous LSCs are not available. The use of allogeneic LSCsrequires strong immunosuppression, which leads to side-effects, and the treatment is not always effective. The alternative and perspective approach to the treatment of severe ocular surface injuries and LSC deficiency is offered by the transplantation of autologous mesenchymal stem cells (MSCs). These cells can be obtained from the bone marrow or adipose tissue of the particular patient, grow well in vitro and can be transferred, using an appropriate scaffold, onto the damaged ocular su
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)