The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10190914" target="_blank" >RIV/00216208:11310/13:10190914 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-1-62703-432-6_13" target="_blank" >http://dx.doi.org/10.1007/978-1-62703-432-6_13</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-62703-432-6_13" target="_blank" >10.1007/978-1-62703-432-6_13</a>

Result language
angličtina
Original language name
The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold
Original language description
The injured or otherwise damaged cornea is healed by limbal stem cells (LSC). If the limbus where LSC reside is also damaged or nonfunctional, the cornea cannot heal properly and this defect leads to impaired vision that can result in blindness. The onlyway to treat total LSC deficiency is by transplantation of limbal tissue or a transfer of LSC. Recently, mesenchymal stem cells (MSC) have been shown as another promising source of stem cells for corneal healing and regeneration. Here, we describe a protocol for the use of polyamide 6/12 nanofiber scaffolds for the growth of MSC and LSC, and for their transfer onto a mechanically damaged ocular surface in the experimental mouse model.
Czech name
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Czech description
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Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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