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Treatment of ocular surface injuries by limbal and mesenchymal stem cells growing on nanofiber scaffolds.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10082456" target="_blank" >RIV/00216208:11310/10:10082456 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/10:00355008 RIV/61389013:_____/10:00355008 RIV/68378050:_____/10:00355008

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Treatment of ocular surface injuries by limbal and mesenchymal stem cells growing on nanofiber scaffolds.

  • Original language description

    The paper describes the use of novel nanofiber scaffolds fabricated from polyamid P6/12 for the growth of limbal stem cells (LSC) and mesechymal stem cellls (MSC). The cells grew on nanofibers comparable well as on plastic surfaces. The cells growing onthese nanofibers were transferred on the damaged ocular surface in experimental mouse nodel where their trafic from the nanofibers onto ocular surface was monitored. The transferred cells supported a healing process after ocular injury and significantlyinhibited a local inflammatory reaction. The results thus showed that LSC and MSC growing on nanofiber scaffolds can be successfully used for the treatment of ocular surface injuries and limbal stem cell deficiencies.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cell Transplantation

  • ISSN

    0963-6897

  • e-ISSN

  • Volume of the periodical

    19

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000285442700006

  • EID of the result in the Scopus database