Nonaqueous emulsion polymerization: A practical synthetic route for the production of molecularly imprinted nanospheres

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10191296" target="_blank" >RIV/00216208:11310/13:10191296 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/pola.26402" target="_blank" >http://dx.doi.org/10.1002/pola.26402</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/pola.26402" target="_blank" >10.1002/pola.26402</a>

Result language

angličtina

Original language name

Nonaqueous emulsion polymerization: A practical synthetic route for the production of molecularly imprinted nanospheres

Original language description

Monodisperse, molecularly imprinted nanospheres were synthesized by nonaqueous (mini)emulsion polymerization using a standard monomer mixture of methacrylic acid and ethylene dimethacrylate containing the drug propranolol as a template. The preparation conditions (solvent, amount of surfactant, and amount of employed template) were extensively varied in order to assess their effect on the properties of the resulting polymer nanoparticles. The molecular recognition capability of the nanospheres was evaluated in batch rebinding experiments, and the effect of the nanosphere preparation conditions as well as of the reaction conditions was investigated. In this way, optimal preparation protocols for molecularly imprinted nanoparticles under nonaqueous conditions with the use of a nonionic emulsifier were identified, which lead to nanospheres with a diameter of around 100 nm having an enhanced capacity of specific template rebinding compared to both nonimprinted nanospheres and to particles

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Polymer Science, Part A: Polymer Chemistry

ISSN

0887-624X

e-ISSN

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Volume of the periodical

51

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

267-274

UT code for WoS article

000312448800005

EID of the result in the Scopus database

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