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Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10271756" target="_blank" >RIV/00216208:11310/14:10271756 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388963:_____/14:00429964

  • Result on the web

    <a href="http://dx.doi.org/10.1002/anie.201402370" target="_blank" >http://dx.doi.org/10.1002/anie.201402370</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/anie.201402370" target="_blank" >10.1002/anie.201402370</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases

  • Original language description

    5-[(2-Nitrobenzyl) oxymethyl]-2'-deoxyuridine 5'-O-triphosphate was used for polymerase (primer extension or PCR) synthesis of photocaged DNA that is resistant to the cleavage by restriction endonucleases. Photodeprotection of the caged DNA released 5-hydroxymethyluracil-modified nucleic acids, which were fully recognized and cleaved by restriction enzymes.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA14-04289S" target="_blank" >GA14-04289S: Modifications and bioorthogonal reactions in the major groove of DNA for regulation of protein binding and gene expression</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Angewandte Chemie - International Edition

  • ISSN

    1433-7851

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    26

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    4

  • Pages from-to

    6734-6737

  • UT code for WoS article

    000338021600028

  • EID of the result in the Scopus database