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Determination of bromhexine at a glassy carbon paste electrode using differential pulse voltammetry and flow injection analysis with amperometric detection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10312012" target="_blank" >RIV/00216208:11310/15:10312012 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s00706-015-1469-9" target="_blank" >http://dx.doi.org/10.1007/s00706-015-1469-9</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00706-015-1469-9" target="_blank" >10.1007/s00706-015-1469-9</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination of bromhexine at a glassy carbon paste electrode using differential pulse voltammetry and flow injection analysis with amperometric detection

  • Original language description

    New electrochemical methods for the determination of bromhexine based on differential pulse voltammetry (DPV) and flow injection analysis with amperometric detection (FIA-ED) were developed using a glassy carbon paste electrode. Optimal supporting electrolyte for DPV measurement was methanol/Britton-Robinson buffer pH 9 (80:20, v/v). In the case of FIA-ED, optimal conditions were as follows: detection potential +1.1 V, flow rate 1.0 cm(3) min(-1), injected volume 0.1 cm(3), and carrier solution methanol-ten times diluted B-R buffer of pH 9 (80:20, v/v). Detection limit was 2.0 x 10(-6) mol dm(-3) for DPV and 3.1 x 10(-7) mol dm(-3) for FIA-ED. The applicability of the newly developed methods was verified by the determination of bromhexine in pharmaceutical preparations (tablets of Bromhexin-EGIS and Bromhexin 8 BC).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Monatshefte für Chemie

  • ISSN

    0026-9247

  • e-ISSN

  • Volume of the periodical

    146

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    AT - AUSTRIA

  • Number of pages

    5

  • Pages from-to

    1211-1215

  • UT code for WoS article

    000358163800003

  • EID of the result in the Scopus database

    2-s2.0-84927555965