Day-to-day variability of toxic events induced by organic compounds bound to size segregated atmospheric aerosol

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10313677" target="_blank" >RIV/00216208:11310/15:10313677 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/15:00451351 RIV/00027162:_____/15:#0001343
Result on the web
<a href="http://dx.doi.org/10.1016/j.envpol.2015.03.024" target="_blank" >http://dx.doi.org/10.1016/j.envpol.2015.03.024</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.envpol.2015.03.024" target="_blank" >10.1016/j.envpol.2015.03.024</a>

Result language
angličtina
Original language name
Day-to-day variability of toxic events induced by organic compounds bound to size segregated atmospheric aerosol
Original language description
This study quantified the temporal variability of concentration of carcinogenic polycyclic aromatic hydrocarbons (c-PAHs), genotoxicity, oxidative DNA damage and dioxin-like activity of the extractable organic matter (EOM) of atmospheric aerosol particles of aerodynamic diameter (d(ae), mu m) coarse (1 < d(ae) < 10), upper- (0.5 < d(ae) < 1) and lower-accumulation (0.17 < d(ae) < 0.5) and ultrafine (<0.17) fractions. The upper accumulation fraction formed most of the aerosol mass for 22 of the 26 studydays and contained 44% of total c-PAHs, while the ultrafine fraction contained only 11%. DNA adduct levels suggested a crucial contribution of c-PAHs bound to the upper accumulation fraction. The dioxin-like activity was also driven primarily by c-PAH concentrations. In contrast, oxidative DNA damage was not related to c-PAHs, as a negative correlation with c-PAHs was observed. These results suggest that genotoxicity and dioxin-like activity are the major toxic effects of organic compoun
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DI - Pollution and air control
OECD FORD branch
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Project
<a href="/en/project/GBP503%2F12%2FG147" target="_blank" >GBP503/12/G147: Centre for studies on toxicity of nanoparticles</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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