An acellular assay to assess the genotoxicity of complex mixtures of organic pollutants bound on size segregated aerosol. Part I: DNA adducts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F10%3A00347664" target="_blank" >RIV/68378041:_____/10:00347664 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/10:10081467
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
An acellular assay to assess the genotoxicity of complex mixtures of organic pollutants bound on size segregated aerosol. Part I: DNA adducts
Original language description
The genotoxicity of the organic extracts (EOMs) from three size fractions of aerosols (ranging from 0.17 to 10?m and collected in 4 localities differing in the extent of pollution) was compared using the analysis of total DNA adducts induced in an acellular assay with/without metabolic activation. It was found that most of the observed genotoxicity was connected with a fine particulate matter fraction (<1?m). These fine fractions bound the highest amount of c-PAHs in all aerosol sites, which might be related to their higher specific surface. As for aerosol mass, both fine and condensational fractions are effective carriers of c-PAHs. Similarly, the DNA adduct levels per m3 of air were highest for the fine fraction and a strong correlation was found between the c-PAHs and DNA adduct levels induced by EOMs in all the localities and for various size fractions.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Toxicology Letters
ISSN
0378-4274
e-ISSN
—
Volume of the periodical
198
Issue of the periodical within the volume
1
Country of publishing house
IE - IRELAND
Number of pages
8
Pages from-to
—
UT code for WoS article
000282855300002
EID of the result in the Scopus database
—