NtGNL1a ARF-GEF acts in endocytosis in tobacco cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10314686" target="_blank" >RIV/00216208:11310/15:10314686 - isvavai.cz</a>

Alternative codes found

RIV/61389030:_____/15:00451390

Result on the web

<a href="http://dx.doi.org/10.1186/s12870-015-0621-3" target="_blank" >http://dx.doi.org/10.1186/s12870-015-0621-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12870-015-0621-3" target="_blank" >10.1186/s12870-015-0621-3</a>

Result language

angličtina

Original language name

NtGNL1a ARF-GEF acts in endocytosis in tobacco cells

Original language description

Background: Processes of anterograde and retrograde membrane trafficking play an important role in cellular homeostasis and dynamic rearrangements of the plasma membrane (PM) in all eukaryotes. These processes depend on the activity of adenosine ribosylation factors (ARFs), a family of GTP-binding proteins and their guanine exchange factors (GEFs). However, knowledge on the function and specificity of individual ARF-GEFs for individual steps of membrane trafficking pathways is still limited in plants. Results: In this work, treatments with various trafficking inhibitors showed that the endocytosis of FM 4-64 is largely dynamin-dependent and relies on proteins containing endocytic tyrosine-based internalization motif and intact cytoskeleton. Interestingly, brefeldin A (BFA), reported previously as an inhibitor of anterograde membrane trafficking in plants, appeared to be the most potent inhibitor of endocytosis in tobacco. In concert with this finding, we demonstrate that the point muta

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC Plant Biology

ISSN

1471-2229

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

listopad 2015

Country of publishing house

GB - UNITED KINGDOM

Number of pages

14

Pages from-to

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UT code for WoS article

000364277700001

EID of the result in the Scopus database

2-s2.0-84959538017