Wnt Signaling Cascades and the Roles of Syndecan Proteoglycans
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10314873" target="_blank" >RIV/00216208:11310/15:10314873 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1369/0022155415586961" target="_blank" >http://dx.doi.org/10.1369/0022155415586961</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1369/0022155415586961" target="_blank" >10.1369/0022155415586961</a>
Alternative languages
Result language
angličtina
Original language name
Wnt Signaling Cascades and the Roles of Syndecan Proteoglycans
Original language description
Wnt signaling comprises a group of pathways emanating from the extracellular environment through cell-surface receptors into the intracellular milieu. Wnt signaling cascades can be divided into two main branches, the canonical/beta-catenin pathway and the non-canonical pathways containing the Wnt/planar cell polarity and Wnt/calcium signaling. Syndecans are type I transmembrane proteoglycans with a long evolutionary history, being expressed in all Bilateria and in almost all cell types. Both Wnt pathways have been extensively studied over the past 30 years and shown to have roles during development and in a multitude of diseases. Although the first evidence for interactions between syndecans and Wnts dates back to 1997, the number of studies connectingthese pathways is low, and many open questions remained unanswered. In this review, syndecan's involvement in Wnt signaling pathways as well as some of the pathologies resulting from dysregulation of the components of these pathways are
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0109" target="_blank" >ED1.1.00/02.0109: Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Histochemistry and Cytochemistry
ISSN
0022-1554
e-ISSN
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Volume of the periodical
63
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
465-480
UT code for WoS article
000358596900001
EID of the result in the Scopus database
2-s2.0-84934768245