Two glycerol uptake systems contribute to the high osmotolerance of Zygosaccharomyces rouxii

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10319407" target="_blank" >RIV/00216208:11310/15:10319407 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/15:00446712
Result on the web
<a href="http://dx.doi.org/10.1111/mmi.13048" target="_blank" >http://dx.doi.org/10.1111/mmi.13048</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/mmi.13048" target="_blank" >10.1111/mmi.13048</a>

Result language
angličtina
Original language name
Two glycerol uptake systems contribute to the high osmotolerance of Zygosaccharomyces rouxii
Original language description
The accumulation of glycerol is essential for yeast viability upon hyperosmotic stress. Here we show that the osmotolerant yeast Zygosaccharomyces rouxii has two genes, ZrSTL1 and ZrSTL2, encoding transporters mediating the active uptake of glycerol in symport with protons, contributing to cell osmotolerance and intracellular pH homeostasis. The growth of mutants lacking one or both transporters is affected depending on the growth medium, carbon source, strain auxotrophies, osmotic conditions and the presence of external glycerol. These transporters are localised in the plasma membrane, they transport glycerol with similar kinetic parameters and besides their expected involvement in the cell survival of hyperosmotic stress, they surprisingly both contribute to an efficient survival of hypoosmotic shock and to the maintenance of intracellular pH homeostasis under non-stressed conditions. Unlike STL1 in Sa.cerevisiae, the two Z.rouxiiSTL genes are not repressed by glucose, but their expr
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/GAP503%2F10%2F0307" target="_blank" >GAP503/10/0307: Molecular basis of osmotolerant yeast Z. rouxii, Z. bailii and D. hansenii specific properties and their biotechnological applications</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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