Non-Enzymatic Electrochemistry in Characterization and Analysis of Steroid Compounds

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F17%3A10367358" target="_blank" >RIV/00216208:11310/17:10367358 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1080/10408347.2017.1318694" target="_blank" >https://doi.org/10.1080/10408347.2017.1318694</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10408347.2017.1318694" target="_blank" >10.1080/10408347.2017.1318694</a>

Result language

angličtina

Original language name

Non-Enzymatic Electrochemistry in Characterization and Analysis of Steroid Compounds

Original language description

This review summarizes achievements in electrochemistry-related research of steroid-based compounds in clinical, pharmaceutical, and environmental analysis. Special attention is paid to compounds possessing none or only isolated double bonds at the steroid core. Their direct redox activity is limited to far positive/negative potentials under variety of conditions and electrode materials and relies on the functional groups attached to the steroid skeleton, or as the case may be its double bond or moieties present at the side chain. The possibilities of electroanalytical methods in sterol characterization and analysis are demonstrated in a table with 31 references devoted to direct voltammetric and amperometric methods of oxidation of cholesterol, phytosterols, oxysterols, and related compounds at carbon-based and metal-based nanoparticles modified electrodes, and the reduction of bile acids and their conjugates at mercury-based electrodes, and modified glassy carbon electrodes. Furthermore, methods based on the indirect oxidation of cholesterol using bromine species as a mediator at platinum electrode and non-enzymatic cholesterol biosensors are reviewed. Their drawbacks and benefits are discussed with respect to the challenging task of identification and quantitation of these compounds in biological matrices, otherwise mostly performed using expensive mass spectrometric techniques preceded by a chromatographic separation step.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Critical Reviews in Analytical Chemistry

ISSN

1040-8347

e-ISSN

—

Volume of the periodical

47

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

21

Pages from-to

384-404

UT code for WoS article

000413838900002

EID of the result in the Scopus database

2-s2.0-85019734093