Understanding the Fragmentation Pathways of Carbocyclic Derivatives of Amino Acids by Using Electrospray Ionization Tandem Mass Spectrometry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F19%3A10399572" target="_blank" >RIV/00216208:11310/19:10399572 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=t-5QmNj4Ma" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=t-5QmNj4Ma</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/00032719.2019.1593431" target="_blank" >10.1080/00032719.2019.1593431</a>
Alternative languages
Result language
angličtina
Original language name
Understanding the Fragmentation Pathways of Carbocyclic Derivatives of Amino Acids by Using Electrospray Ionization Tandem Mass Spectrometry
Original language description
Aminoacyl derivatives of aminoadamantanes amantadine and rimantadine have been investigated in regard to their antiviral properties. So far, few studies on the mass spectrometric fragmentation pathway of these compounds have been reported using high-resolution mass spectrometry (HRMS). Two major fragmentation pathways have been observed. For the rimantadine derivatives, losses of rimantadine and N-(1-adamantyl) ethylformamide were described. Similarly, in case of amantadine derivatives, there were losses of amantadine and N-(1-adamantyl) formamide. The loss of the aminoacyl group was common to all of the studied compounds. Understanding the fragmentation mechanism can bring new insight into the characterization of these compounds.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytical Letters
ISSN
0003-2719
e-ISSN
—
Volume of the periodical
52
Issue of the periodical within the volume
13
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
2069-2076
UT code for WoS article
000466010300001
EID of the result in the Scopus database
2-s2.0-85063901632