The effects of toxoplasmosis on sex ratio at birth
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F20%3A10405470" target="_blank" >RIV/00216208:11310/20:10405470 - isvavai.cz</a>
Alternative codes found
RIV/00023752:_____/20:43920462
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=~buP0lBRXD" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=~buP0lBRXD</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.earlhumdev.2019.104874" target="_blank" >10.1016/j.earlhumdev.2019.104874</a>
Alternative languages
Result language
angličtina
Original language name
The effects of toxoplasmosis on sex ratio at birth
Original language description
Toxoplasmosis affects about one third of human population worldwide. It has a wide range of effects on the health, immunity, behaviour, and both prenatal and postnatal outcomes of infected hosts, including humans. Among these effects, stage of infection-specific shifts in secondary sex ratio were described about ten years ago both in humans and in artificially infected mice. In both women and female mice, in the early stage of infection the probability of giving birth of sons significantly increases, up to 260 sons to every 100 daughters. In the late stages of infection, the probability of giving birth to sons markedly decreases to as low as 78 to every 100 daughters. An ecological correlation study shows that the effect of latent toxoplasmosis on human population biology and demography can be large. In fact, the effect of prevalence of toxoplasmosis on a nationwide sex ratio was the third strongest effect from the effects of 15 factors included in the analysis. It has been suggested that toxoplasmosis-associated concentration of steroid hormones or glucose may be the proximal cause in the sex ratio shift. A more parsimonious explanation of the upward secondary sex ratio shift is found in a lower stringency of quality control of embryos, whose side-effect is increased survival rate of the more immunogenic male embryos in immunosuppressed infected females. The most parsimonious explanation of the downward secondary sex ratio shift relies on the Trivers-Willard hypothesis, which predicts an adaptive shift to more daughters in females with impaired health or lower socioeconomic status.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10600 - Biological sciences
Result continuities
Project
<a href="/en/project/GA18-13692S" target="_blank" >GA18-13692S: Conservation of Rh Polymorphism in Modern Humans through Selection Favoring Heterozygotes – The Influence of the Genotype on Fertility and Viability</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Early Human Development
ISSN
0378-3782
e-ISSN
—
Volume of the periodical
141
Issue of the periodical within the volume
February
Country of publishing house
IE - IRELAND
Number of pages
5
Pages from-to
104874
UT code for WoS article
000527923800009
EID of the result in the Scopus database
2-s2.0-85071672712