Poly(2-oxazoline)-based stimulus-responsive (Co)polymers: An overview of their design, solution properties, surface-chemistries and applications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F20%3A10419864" target="_blank" >RIV/00216208:11310/20:10419864 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9k0YQj3MUb" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9k0YQj3MUb</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.progpolymsci.2020.101252" target="_blank" >10.1016/j.progpolymsci.2020.101252</a>
Alternative languages
Result language
angličtina
Original language name
Poly(2-oxazoline)-based stimulus-responsive (Co)polymers: An overview of their design, solution properties, surface-chemistries and applications
Original language description
Pseudopeptidic poly(2-oxazoline)s are a special class of bio-inspired polymers with multiple applications, especially in the field of polymer therapeutics. Unsurprisingly, poly(2-oxazoline) has been extensively studied in recent decades, and pioneering studies on these polymers have shown that nonionic, hydrophilic and thermo-responsive poly(2-oxazoline)s are comparable to and sometimes even more advantageous than poly( ethylene glycol) for biomedical applications. Considering their applications in the biomedical field, stimuli-responsive polymer materials open new opportunities for in vivo applications such as on-demand drug delivery, tissue repairing, biosensing and smart coatings, among others. In this context, this article is a comprehensive review of recent advances in stimuli-responsive polymers/interfaces consisting of poly(2-oxazoline)-based "smart" homopolymer and ( co )polymer materials responsive to different single stimulus or to multiple stimuli. In particular, we focus on the synthesis (design strategies), "smart" solution properties (tuning of cloud points), self-assembly (tuning of nanostructures), surface chemistry (surface grafting strategies, antifouling properties, responsive behaviors) and possible biomedical applications of different stimulus-responsive materials based on functionalized poly(2-oxazoline). Accordingly, this review can be used as a benchmark for biopolymer researchers, thereby helping them design innovative functional poly(2-oxazoline)-based "smart" bio-inspired materials for novel applications by highlighting key research gaps and future research avenues in this dynamic and highly relevant field of research.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
<a href="/en/project/LTAIN19078" target="_blank" >LTAIN19078: Stimuli-Responsive Block Copolymer Based Nanostructured Single-/Multi-component Micelles: Materials and Applications</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Progress in Polymer Science
ISSN
0079-6700
e-ISSN
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Volume of the periodical
106
Issue of the periodical within the volume
July
Country of publishing house
GB - UNITED KINGDOM
Number of pages
46
Pages from-to
101252
UT code for WoS article
000541865400001
EID of the result in the Scopus database
2-s2.0-85085930143