14.11 – Ten-Membered Rings or Larger With One or More Nitrogen Atoms
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F22%3A10437392" target="_blank" >RIV/00216208:11310/22:10437392 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/B978-0-12-818655-8.00128-1" target="_blank" >https://doi.org/10.1016/B978-0-12-818655-8.00128-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-818655-8.00128-1" target="_blank" >10.1016/B978-0-12-818655-8.00128-1</a>
Alternative languages
Result language
angličtina
Original language name
14.11 – Ten-Membered Rings or Larger With One or More Nitrogen Atoms
Original language description
The chapter covers mainly triaza- and tetraazamacrocyles and, among them, derivatives of cyclen and cyclam. The text presents cyclization procedures, protection strategies and further modifications of the azacycles. The main part is devoted to synthetic modification of the ring secondary amine groups with (coordinating) pendant arms. The azacycles mostly serves as complexation agents (ligands, chelators) and their properties are further modified and tuned through donor atoms present in these pendant arms. Ligands containing another reactive group are often conjugated to biological vectors and these bifunctional ligands are highlighted. The text also covers so-called cross-bridged macrocycles. Properties of the compounds in the solid state are demonstrated on selected examples. Finally, metal binding properties of the azacycles and applications of the complexes as MRI contrast agents, radiopharmaceuticals, luminescence probes and paramagnetic labels are briefly discussed.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Eight-membered and larger heterocyclic rings and their fused derivates; other seven-membered rings
ISBN
978-0-12-818656-5
Number of pages of the result
93
Pages from-to
591-683
Number of pages of the book
1002
Publisher name
Elsevier
Place of publication
New York
UT code for WoS chapter
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