Role of the PML nuclear bodies and its associated histones chaperones in the remodeling of mouse polyomavirus minichromosomes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10470052" target="_blank" >RIV/00216208:11310/23:10470052 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/41/" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/41/</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Role of the PML nuclear bodies and its associated histones chaperones in the remodeling of mouse polyomavirus minichromosomes
Original language description
Polyomaviruses (PyVs) are small non-enveloped viruses replicating in the host cell nucleus. Viral replication centers (VRCs) share features with cellular euchromatic or heterochromatic regions, depending on the stage of infection. In the mouse polyomavirus (MPyV) virions, the circular dsDNA genome and cellular histones are present in the form of a condensed minichromosome arranged into 24 nucleosomes. Here we studied the contribution of PML NBs and their chaperone complexes HIRA and ATRX/DAXX in remodeling MPyV chromatin.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů