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Understanding the interplay between MPyV infection and nuclear lamina

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10470055" target="_blank" >RIV/00216208:11310/23:10470055 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.ccsss.cz/index.php/ccsss/issue/view/41/" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/41/</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Understanding the interplay between MPyV infection and nuclear lamina

  • Original language description

    The nuclear lamina (NL) is a dense meshwork of intermediate filaments V, type A lamins (lamin A/C), type B lamins and membrane associated proteins. It is located below the inner nuclear membrane. NL maintains the shape and structural integrity of the nucleus and plays an important role in fine-tuning of DNA related processes, e. g. replication or transcription. Also, it has been suggested to play a role in cell defence against pathogens. DNA viruses evolved mechanisms to exploit NL for their own purposes.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10607 - Virology

Result continuities

  • Project

    <a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů