Voltammetric Detection of Monoamine Neurotransmitters in a Neurobasal Medium

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10478216" target="_blank" >RIV/00216208:11310/23:10478216 - isvavai.cz</a>
Result on the web
<a href="https://www.bestservis.eu/realizovane-akce/42-mem/43/" target="_blank" >https://www.bestservis.eu/realizovane-akce/42-mem/43/</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Voltammetric Detection of Monoamine Neurotransmitters in a Neurobasal Medium
Original language description
The possibility of electroanalytical detection of important neurotransmitters - dopamine and serotonin - in a neuron cultivation medium on boron-doped diamond electrodes was studied and confirmed. The presence of both analytes manifested as a peak on a differential pulse voltammogram within +300 - +450 mV vs. Ag/AgCl reference electrode. Limits of detection as low as 0.2 and 2.0 μM for serotonin and dopamine, respectively, were achieved. The performance of oxidized and polished electrode surfaces was compared. Mechanical polishing resulted in ca. twofold lower limits of detection, but lower reproducibility of measurements at higher concentrations.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Sborník přednášek mezinárodní odborné konference 42. Moderní Elektrochemické Metody
ISBN
978-80-908947-0-9
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
124-128
Publisher name
Lenka Srsenová - BEST Servis Ústí nad Labem
Place of publication
Ústí nad Labem
Event location
Jetrichovice, Česká republika
Event date
May 22, 2023
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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