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Inhibition of HBsAg secretion by a novel autophagy inducer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F24%3A10477360" target="_blank" >RIV/00216208:11310/24:10477360 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.virology.cz/" target="_blank" >https://www.virology.cz/</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Inhibition of HBsAg secretion by a novel autophagy inducer

  • Original language description

    Chronic hepatitis B (CHB) is a viral liver infection caused by hepatitis B virus (HBV), affecting over 300 million people world-wide. Untreated CHB can lead to liver cirrhosis and hepatocellular carcinoma, causing over 800,000 deaths annually. Current nucleot(s)ide analogue-based therapies effectively slow disease progression and reduce viral load, but require life-long application. Pegylated interferon alpha therapy clears the virus in a small percentage of patients, but has serious side effects. Therefore, a universally effective and definitive cure of CHB is still elusive.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10607 - Virology

Result continuities

  • Project

    <a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů