Novel autophagy inducer inhibits hepatitis B virus S antigen secretion
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F24%3A10486083" target="_blank" >RIV/00216208:11310/24:10486083 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Novel autophagy inducer inhibits hepatitis B virus S antigen secretion
Original language description
Chronic hepatitis B (CHB), a liver infection caused by the hepatitis B virus (HBV), affects more than 300 million people worldwide. If left untreated, CHB can progress to liver cirrhosis and hepatocellular carcinoma, resulting in over 800,000 deaths annually. While current therapies based on nucleot(s)ide analogues effectively slow disease progression and reduce viral load, they require lifelong adinistration. Pegylated interferon alpha therapy can achieve clearance in a small fraction of patients but is associated with significant side effects.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10600 - Biological sciences
Result continuities
Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů