Enantioselective Desymmetrization by Chiral Bifunctional H-Bonding Organocatalysts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F25%3A10513947" target="_blank" >RIV/00216208:11310/25:10513947 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=F2gUJ8.m6l" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=F2gUJ8.m6l</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/chem.202502172" target="_blank" >10.1002/chem.202502172</a>
Alternative languages
Result language
angličtina
Original language name
Enantioselective Desymmetrization by Chiral Bifunctional H-Bonding Organocatalysts
Original language description
Enantioselective desymmetrization has emerged as an effective method for generating highly enriched chiral molecules from achiral compounds. In recent years, organocatalysis has played an increasingly prominent role in this field, offering metal-free and environmentally benign alternatives to traditional asymmetric catalysis. This review focuses on organocatalytic approaches in desymmetrization reactions that utilize bifunctional hydrogen activation of the substrate by a chiral organocatalyst. The most common types of chiral bifunctional organocatalysts include cinchona alkaloids and their derivatives, such as thioureas, sulfonamides, and squaramides. The following text provides an overview of the enantioselective desymmetrization methods that have been described to date for meso-anhydrides, meso-diols, amines, small heterocyclic rings, and various carbonyl compound derivatives.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
<a href="/en/project/GA24-12575S" target="_blank" >GA24-12575S: Organocatalytic Central-to-Axial and Central/Axial-to-Planar Chirality Transfer (ORCA PLATE)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemistry - A European Journal
ISSN
0947-6539
e-ISSN
1521-3765
Volume of the periodical
31
Issue of the periodical within the volume
61
Country of publishing house
DE - GERMANY
Number of pages
22
Pages from-to
e02172
UT code for WoS article
001588633400001
EID of the result in the Scopus database
2-s2.0-105018010910