Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F99%3A00003166" target="_blank" >RIV/00216208:11310/99:00003166 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.

Original language description

Aristolactam I is a detoxication metabolite of carcinogenic alkaloid aristolochic acid I. After activation of this metabolite by peroxidase and cytochrome P450 the DNA adduts are formed.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/VS96141" target="_blank" >VS96141: Investigation of molecular architecture and molecular interactions of biologically important proteins and their protein domains</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

1999

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Experimental and Toxicologic Pathology

ISSN

0940-2993

e-ISSN

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Volume of the periodical

51

Issue of the periodical within the volume

4-5

Country of publishing house

DE - GERMANY

Number of pages

4

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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