SETTER: web server for RNA structure comparison

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F12%3A10124055" target="_blank" >RIV/00216208:11320/12:10124055 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/12:43893841 RIV/60461373:22340/12:43893841
Result on the web
<a href="http://dx.doi.org/10.1093/nar/gks560" target="_blank" >http://dx.doi.org/10.1093/nar/gks560</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/nar/gks560" target="_blank" >10.1093/nar/gks560</a>

Result language
angličtina
Original language name
SETTER: web server for RNA structure comparison
Original language description
The recent discoveries of regulatory non-coding RNAs changed our view of RNA as a simple information transfer molecule. Understanding the architecture and function of active RNA molecules requires methods for comparing and analyzing their 3D structures.While structural alignment of short RNAs is achievable in a reasonable amount of time, large structures represent much bigger challenge. Here, we present the SETTER web server for the RNA structure pairwise comparison utilizing the SETTER (SEcondary sTructure-based TERtiary Structure Similarity Algorithm) algorithm. The SETTER method divides an RNA structure into the set of non-overlapping structural elements called generalized secondary structure units (GSSUs). The SETTER algorithm scales as O(n(2)) with the size of a GSSUs and as O(n) with the number of GSSUs in the structure. This scaling gives SETTER its high speed as the average size of the GSSU remains constant irrespective of the size of the structure. However, the favorable spee
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
IN - Informatics
OECD FORD branch
—

Project
<a href="/en/project/GAP202%2F11%2F0968" target="_blank" >GAP202/11/0968: Large-scale Nonmetric Similarity Search in Complex Domains</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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