Efficient RNA pairwise structure comparison by SETTER method

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F12%3A10124054" target="_blank" >RIV/00216208:11320/12:10124054 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22310/12:43893493

Result on the web

<a href="http://dx.doi.org/10.1093/bioinformatics/bts301" target="_blank" >http://dx.doi.org/10.1093/bioinformatics/bts301</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/bioinformatics/bts301" target="_blank" >10.1093/bioinformatics/bts301</a>

Result language

angličtina

Original language name

Efficient RNA pairwise structure comparison by SETTER method

Original language description

Motivation: Understanding the architecture and function of RNA molecules requires methods for comparing and analyzing their 3D structures. Although a structural alignment of short RNAs is achievable in a reasonable amount of time, large structures represent much bigger challenge. However, the growth of the number of large RNAs deposited in the PDB database calls for the development of fast and accurate methods for analyzing their structures, as well as for rapid similarity searches in databases. Results: In this article a novel algorithm for an RNA structural comparison SETTER (SEcondary sTructure-based TERtiary Structure Similarity Algorithm) is introduced. SETTER uses a pairwise comparison method based on 3D similarity of the so-called generalized secondary structure units. For each pair of structures, SETTER produces a distance score and an indication of its statistical significance. SETTER can be used both for the structural alignments of structures that are already known to be hom

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

IN - Informatics

OECD FORD branch

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Project

<a href="/en/project/GAP202%2F11%2F0968" target="_blank" >GAP202/11/0968: Large-scale Nonmetric Similarity Search in Complex Domains</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BIOINFORMATICS

ISSN

1367-4803

e-ISSN

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Volume of the periodical

28

Issue of the periodical within the volume

14

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

1858-1864

UT code for WoS article

000306136100009

EID of the result in the Scopus database

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