Antimicrobial peptide from the eusocial bee Halictus sexcinctus interacting with model membranes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F12%3A10125560" target="_blank" >RIV/00216208:11320/12:10125560 - isvavai.cz</a>

Alternative codes found

RIV/61388963:_____/12:00378834

Result on the web

<a href="http://dx.doi.org/10.1155/2012/840956" target="_blank" >http://dx.doi.org/10.1155/2012/840956</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2012/840956" target="_blank" >10.1155/2012/840956</a>

Result language

angličtina

Original language name

Antimicrobial peptide from the eusocial bee Halictus sexcinctus interacting with model membranes

Original language description

Halictine-1 (Hal-1)-a linear antibacterial dodecapeptide isolated from the venom of the eusocial bee Halictus sexcinctus - has been subjected to a detailed spectroscopic study including circular dichroism, fluorescence, and vibrational spectroscopy. We investigated Hal-1 ability to adopt an amphipathic alpha-helical structure upon interaction with model lipid-based bacterial membranes (phosphatidylcholine/phosphatidylglycerol-based large unilamellar vesicles and sodium dodecylsulfate micelles) and helixinducing components (trifluoroethanol). It was found that Hal-1 responds sensitively to the composition of the membrane model and to the peptide/lipid ratio. The amphipathic nature of the helical Hal-1 seems to favour flat charged surfaces of the modellipid particles over the nondirectional interaction with trifluoroethanol. Increasing fraction of polyproline II type conformation was detected at low peptide/lipid ratios.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

<a href="/en/project/GAP208%2F10%2F0376" target="_blank" >GAP208/10/0376: Interaction of antibacterial peptides with the model membranes and possibility of the prediction of their biological activity</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

SPECTROSCOPY-AN INTERNATIONAL JOURNAL

ISSN

0712-4813

e-ISSN

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Volume of the periodical

27

Issue of the periodical within the volume

5-6

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

6

Pages from-to

497-502

UT code for WoS article

000306505500028

EID of the result in the Scopus database

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