A virtual reality task based on animal research - spatial learning and memory in patients after the first episode of schizophrenia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F14%3A10284163" target="_blank" >RIV/00216208:11320/14:10284163 - isvavai.cz</a>

Alternative codes found

RIV/67985823:_____/14:00428984 RIV/00216208:11120/14:43908569 RIV/00023752:_____/14:43914583

Result on the web

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00157" target="_blank" >http://dx.doi.org/10.3389/fnbeh.2014.00157</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00157" target="_blank" >10.3389/fnbeh.2014.00157</a>

Result language

angličtina

Original language name

A virtual reality task based on animal research - spatial learning and memory in patients after the first episode of schizophrenia

Original language description

Objectives: Cognitive deficit is considered to be a characteristic feature of schizophrenia disorder. A similar cognitive dysfunction was demonstrated in animal models of schizophrenia. However, the poor comparability of methods used to assess cognitionin animals and humans could be responsible for low predictive validity of current animal models. In order to assess spatial abilities in schizophrenia and compare our results with the data obtained in animal models, we designed a virtual analog of the Morris water maze (MWM), the virtual Four Goals Navigation (vFGN) task. Methods: Twenty-nine patients after the first psychotic episode with schizophrenia symptoms and a matched group of healthy volunteers performed the vFGN task. They were required to find and remember four hidden goal positions in an enclosed virtual arena. The task consisted of two parts. The Reference memory (RM) session with a stable goal position was designed to test spatial learning. The Delayed-matching-to-place (D

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in Behavioral Neuroscience

ISSN

1662-5153

e-ISSN

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Volume of the periodical

8

Issue of the periodical within the volume

Neuveden

Country of publishing house

CH - SWITZERLAND

Number of pages

15

Pages from-to

1-15

UT code for WoS article

000336793300001

EID of the result in the Scopus database

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