Ultrasonic Formation of Copper/Iron Graphene Oxide for Ketorolac Delivery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F19%3A10405970" target="_blank" >RIV/00216208:11320/19:10405970 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=99ptnfvQco" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=99ptnfvQco</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1142/S0219581X19400726" target="_blank" >10.1142/S0219581X19400726</a>
Alternative languages
Result language
angličtina
Original language name
Ultrasonic Formation of Copper/Iron Graphene Oxide for Ketorolac Delivery
Original language description
New accessible sonochemical methods were developed for the functionalization of synthesized graphene oxide (GO) with copper/iron compounds and drug intercalation into their structure in aqueous solution at ambient conditions by using ultrasound (20 kHz) treatment. The sonochemical formation mechanism of a new nanomaterial was revealed through the structural analysis of three types of nanocomposites: (i) copper@graphene oxide, (ii) copper/iron@graphene oxide and (iii) iron@graphene oxide. Unique copper/iron-modified graphene oxide nanocomposites can be used as nanocarriers for the anti-inflammatory drug (ketorolac) delivery in aqueous solution due to the reduced submicron size and enlarged surface area. Disintegration of the ultrasonically intercalated ketorolac followed the exponential decay curve fit at higher pH values of the aqueous solution with a higher decay constant observed in copper/iron-modified graphene oxide nanocomposites.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10305 - Fluids and plasma physics (including surface physics)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Nanoscience
ISSN
0219-581X
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
3-4
Country of publishing house
SG - SINGAPORE
Number of pages
4
Pages from-to
1940072
UT code for WoS article
000472775200073
EID of the result in the Scopus database
2-s2.0-85068181153