Gene polymorphisms (G82S,1704G/T, 2184A/G and 2245G/A) in the receptor of advanced glycation end products (RAGE) with plaque psoriasis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00005742" target="_blank" >RIV/00216224:14110/02:00005742 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Gene polymorphisms (G82S,1704G/T, 2184A/G and 2245G/A) in the receptor of advanced glycation end products (RAGE) with plaque psoriasis

Original language description

Having in mind relations between oxidative stress, psoriasis and common disorders, associations of polymorphisms in gene coding for RAGE with plaque psoriasis considering personal history of diabetes mellitus, cardiovascular disorders, cancer and allergywere investigated.Allele frequencies and genotype combinations of the four polymorphisms in RAGE gene (6p 21.3, G82S, 1704G/T, 2184A/G and 2245A/G) were compared in a case-control study comprising 272 subjects (130 patients with plaque psoriasis and 142healthy control subjects of comparable age and sex distribution). Polymerase chain reaction with subsequent restriction analysis were used for detection of allele variants. No correlations of alleles and/or genotypes of all examined RAGE polymorphism with positive familiar history of psoriasis and/or early onset of psoriasis manifestation (less than 40 years) were found. The G82S, 1704G/T and 2245A/G RAGE polymorphisms were associated neither with plaque psoriasis nor with personal hist

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FO - Dermatology and venereology

OECD FORD branch

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Project

<a href="/en/project/VS96097" target="_blank" >VS96097: Molecular pathophysiology of selected multigenic related to civilization diseases</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Archives of Dermatological Research

ISSN

0340-3696

e-ISSN

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Volume of the periodical

294

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

4

Pages from-to

127

UT code for WoS article

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EID of the result in the Scopus database

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