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Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00007139" target="_blank" >RIV/00216224:14110/02:00007139 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model

  • Original language description

    The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many recent experimental works, it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. In our previous work [27], the basic properties of TAT-system were formulated and preliminary simulations characterizing its effect on cellular electrical activity realised. In this article, we describe the design of a more complex model of ventricular myocyte based mostly on data from guinea pig. The model integrates the description of electrical activity of surface and tubular membranes with the detailed descriptionof mechanisms controlling the intracellular and tubular ion concentrations.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2002

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Engineering Mechanics 2002

  • ISBN

    80-86246-18-3

  • ISSN

  • e-ISSN

  • Number of pages

    2

  • Pages from-to

    1-2

  • Publisher name

    Národní konference s mezinárodní účastí

  • Place of publication

    Svratka

  • Event location

    Svratka

  • Event date

    Jan 1, 2002

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article