Development of antifungals against the black yeast

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00008025" target="_blank" >RIV/00216224:14110/03:00008025 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Development of antifungals against the black yeast
Original language description
Aureobasidium pullulans is an unusual yeast. Although its usual habitat is decaying wood, it can be an opportunistic pathogen of plants, and also animals, including humans. It has been found in a number of very unpleasant infections, usually in patientswho are already immunocompromised. Treating these conditions is difficult, because there are only subtle differences between a fungus and a human that can be exploited for antifungal therapies. Researchers at Masaryk University in the Czech Republic haveworked with colleagues at the Research Center for Pathogenic Fungi and Microbial Toxicoses at Chiba University in Japan to study the development and organisation of Aureobasidium pullulans, hoping to find clues for new antifungal drugs. Their observations are also intrinsically interesting because, unlike other yeasts, the cells in one culture can exist in a variety of sizes and shapes with variable numbers of nuclei. In optimal growth conditions, with ample nutrients and aeration, the
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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