LIGNANS OF SCHISANDRA CHINENSIS: ANALYSIS IN PLANT CELL CULTURE AND ANTIPROLIFERATIVE ACTIVITY

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00008061" target="_blank" >RIV/00216224:14110/03:00008061 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
LIGNANS OF SCHISANDRA CHINENSIS: ANALYSIS IN PLANT CELL CULTURE AND ANTIPROLIFERATIVE ACTIVITY
Original language description
Dibenzocyclo[a,c]diene lignans occur exclusively in genera Schisandra and Kadsura (Schisandraceae/Magnoliaceae). Schisnadra chinensis is well-known medicinal plants of traditional Chinese medicine in which fruits have been used as tonic and antitusic. These lignans have been shown to possess a broad range of biological effects, including antivirral, antioxidative and hepatoprotective activities. Content of lignans in fruits of the plants is relatively low (~1 %) and is composed of at least thirty lignans. Moreover, contents of individual lignans considerably vary from plant to plant. Plant cell culture may represent a solution of the supply of these lignans. We determined the production of lignans in cell culture of S. chinensis using HPLC. Our preliminary results showed, that amount of lignans in plant cell cultures was lower than that in fruits and leaves. The main lignan in samples of cell cultures was deoxyschizandrin, its maximum yield reached 0.13 % based on biomass dry weight. T
Czech name
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Czech description
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Project
<a href="/en/project/GA521%2F02%2F1129" target="_blank" >GA521/02/1129: The use of biotechnological methods in secondary metabolite production, breeding and micropropagation of medical plant Schizandra chinensis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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