Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00009236" target="_blank" >RIV/00216224:14110/03:00009236 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats
Original language description
In the present study, modulation of the reinforcing effects of methamphetamine by the non-selective 5-HT2 receptor agonist alpha-methyl-serotonin was ascertained using the method of i.v. self-administration in rats. In summary, our findings suggest that5-HT2 receptor activation might attenuate methamphetamine self-administration. These results are in accordance with the findings of Munzar et al. (1999) indicating that 5-HT mediation of discriminative stimulus actions of methamphetamine appears to be involved to a big extent in stimulation at 5-HT2A/2C receptors.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Abstract Book of Sixth IBRO World Congress of Neuroscience
ISBN
80-239-0887-1
ISSN
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e-ISSN
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Number of pages
1
Pages from-to
205-205
Publisher name
Neuveden
Place of publication
Prague (Czech Republic)
Event location
Prague, Czech Republic
Event date
Jul 10, 2003
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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