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Pretreatment with alpha-methyl-5-hydroxytryptamine attenuates methamphetamine i.v. self-administration in rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00008734" target="_blank" >RIV/00216224:14110/03:00008734 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Pretreatment with alpha-methyl-5-hydroxytryptamine attenuates methamphetamine i.v. self-administration in rats

  • Original language description

    To ascertain the involvement of 5-HT2 receptor subtype in rewarding properties of methamphetamine (METH), non-selective 5-HT2 agonist alpha-methyl-5-hydroxytryptamine was tested for its ability to influence METH "i.v. self-administration" in rats. From our results, 5-HT2 receptor activation slightly attenuated METH self-administration. This ability can be hypothetically mediated via supression of either "craving" or sensitization mechanisms.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2003

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    PROGRAMME AND ABSTRACTS of 5th NEUROCHEMISTRY WINTER CONFERENCE

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    30

  • Publisher name

    University of Innsbruck

  • Place of publication

    Sölden (Ötztal), Rakousko

  • Event location

    April 5 - 10, 2003, Sölden (Ötztal), Rakousko

  • Event date

    Jan 1, 2003

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article