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Age related changes of baroreflex sensitivity in children and adolescents

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00013798" target="_blank" >RIV/00216224:14110/05:00013798 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    čeština

  • Original language name

    Age related changes of baroreflex sensitivity in children and adolescents

  • Original language description

    The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p&lt;0.001). BRS correlated with mean IBI (p&lt;0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity

  • Czech name

    Age related changes of baroreflex sensitivity in children and adolescents

  • Czech description

    The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p&lt;0.001). BRS correlated with mean IBI (p&lt;0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR8006" target="_blank" >NR8006: Automonous circulations functions,myocard and cardiorespiratory functions in children and adolescents after malignancy treatment.</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů