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Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00018695" target="_blank" >RIV/00216224:14110/06:00018695 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/06:#0000323

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?

  • Original language description

    The aim of the study was to determine changes of baroreflex sensitivity (BRS/BRSf) in humans between 11 and 20 years of age. Beat-by-beat values of inter-beat intervals (IBI) or heart rate, and systolic and diastolic blood pressures were measured for 5 min in 415 healthy subjects. BRS did not correlate with age, but BRSf significantly decreased (p&lt;0.001). BRS correlated with mean IBI (p&lt;0.001), but BRSf was IBI-independent. Results of multiregression equations were: BRS=1.37-0.56*age+0.02*IBI (p&lt;0.001 for BRS vs. age and for BRS vs. IBI); BRSf=34.74?0.97*age-0.001*IBI (p&lt;0.001 only for BRS vs. age). The limits of BRS: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.7, and limits for BRSf: 5th percentile - 8.5 mHz/mmHg; 50th - 16.4; 95th- 33.6. Conclusion: IBI-dependent BRS was unchanged in the particular age groups, but the standardization of BRS on IBI was decreased with age. BRSf was IBI-independent and better reflected the development of the baroreflex sensitivity.

  • Czech name

    Je možno detekovat vývoj citlivosti baroreflexu u člověka ve věku 11 až 20 let?

  • Czech description

    Cílem práce bylo ukázat vývoj citlivosti baroreflexu (BRS[ms/mmHg]/BRSf[mHz/mmHg]) u člověka ve věku 11 ? 20 let. U 415 zdravých osob byly po dobu 5 min. zaznamenávány tep po tepu hodnoty srdečních intervalů (SI), popř. srdeční frekvence, systolického adiastolického tlaku. BRS nekorelovalo s věkem, naopak BRSf s věkem významně klesalo (p&lt;0.001). BRS korelovalo významně s SI (p&lt;0.001), ale BRSf bylo na IBI nezávislé. Výsledky multiregresní analýzy: BRS=1,37-0,56*věk+0,02*SI (p&lt;0.001 pro BRS vs.věk a pro BRS vs. SI); BRSf=34,74?0,97*věk-0.001*SI (p&lt;0.001 pouze pro BRS vs. věk). Limity BRS: 5. percentil ? 3,9 ms/mmHg; 50. ? 9,1; 95. ? 18,7, a limity pro BRSf: 5. percentil ? 8,5 mHz/mmHg; 50. ? 16,4; 95. ? 33,6. Závěr: Na SI závislá BRS bylav jednotlivých věkových podskupinách nezměněná, ale po standardizaci BRS na IBI byl prokázán pokles s věkem. BRSf, která byla na SI nezávislá, lépe odrážela vývoj citlivosti baroreflexu.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR8006" target="_blank" >NR8006: Automonous circulations functions,myocard and cardiorespiratory functions in children and adolescents after malignancy treatment.</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Canadian Journal of Physiology and Pharmacology

  • ISSN

    1205-7541

  • e-ISSN

  • Volume of the periodical

    84

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    CA - CANADA

  • Number of pages

    9

  • Pages from-to

    1275-1283

  • UT code for WoS article

  • EID of the result in the Scopus database