Antioxidant and DNA reparation enzyme genetic polymorphism as a pathogenic factor of diabetic nephropathy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00015889" target="_blank" >RIV/00216224:14110/06:00015889 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Antioxidant and DNA reparation enzyme genetic polymorphism as a pathogenic factor of diabetic nephropathy
Original language description
Catalase is an endogenous antioxidant enzyme neutralizing hydrogen peroxide and is induced by oxidative challenge. A -262C/T polymorphism in the promoter region of the gene is a functional variant modulating activity of the enzyme. Ascertained association suggests that variability in the CAT gene may confer a modest genetic risk for the development of diabetic nephropathy in type 2 diabetics in Czech population.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů