Recognition of pore-forming colicin Y by its cognate immunity protein.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00016068" target="_blank" >RIV/00216224:14110/06:00016068 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Recognition of pore-forming colicin Y by its cognate immunity protein.
Original language description
Construction of hybrid immunity genes between colicin U (cui) and Y (cyi) immunity genes and site-directed mutagenesis of cyi were used to identify amino-acid residues of the colicin Y immunity protein (Cyi) involved in recognition of colicin Y. These amino-acid residues were localized close to the cytoplasmic site of the Cyi transmembrane helices T3 (S104, S107, F110, A112) and T4 (A159). Mutations in cui, which converted Cui sequence to Cyi sequence in positions 104, 107, 110, 112 and 159, resulted inan immunity gene that also conferred (besides immunity to colicin U) a high degree of immunity to colicin Y.
Czech name
Rekognice pore-forming domény kolicinu Y jeho imunitním proteinem.
Czech description
Je posána a diskutována rekognice pore-forming domény kolicinu Y jeho imunitním proteinem.

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/GA310%2F03%2F1091" target="_blank" >GA310/03/1091: Mapping of the colicin route to the sensitive and immune bacterium: studies on colicin-receptor and colicin-immunity protein interaction</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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