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EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00016959" target="_blank" >RIV/00216224:14110/06:00016959 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY

  • Original language description

    We followed effect of anthracycline therapy on physical activity, body and cardiovascular parameters in children treated for malignant tumor. We examined 21 subjects after antitumor therapy (M; 15.5b3.2 years) and 32 healthy subjects (Co; 15.7b2.1 years). In group M, 8 subjects had a non-cardiotoxic therapy (A0), and 13 children were treated with anthracyclines (A+). In group A+ vs. A0 and Co, we found significantly lower SBP. A+ compared with Co had higher BRSf; lower weight and height; lower total physical activity and physical activity related to 1 kg of body weight. In whole group M, we found negative correlation between dose of anthracyclines and SBP and total physical activity. The multiple regression in group M shown that SBP was significantly related to the duration of period without antitumor therapy and to the dosage of anthracyclines. BRSf significantly correlated with body weight, physical activity related to 1 kg of body weight, time since therapy and SBP.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR8006" target="_blank" >NR8006: Automonous circulations functions,myocard and cardiorespiratory functions in children and adolescents after malignancy treatment.</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů