Baroreflex Sensitivity And A1166C Polymorphism In AT1 Receptor Gene

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F07%3A00023323" target="_blank" >RIV/00216224:14110/07:00023323 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Baroreflex Sensitivity And A1166C Polymorphism In AT1 Receptor Gene

Original language description

Decreased baroreflex sensitivity (BRS in ms/mmHg; BRSf in mHz/mmHg) contributes to the development of hypertension and to the risk of sudden cardiac death in patients after myocardial infarction. The aim of this study was to evaluate association of single nucleotide polymorphism A1166C in angiotensin II type 1 receptor (AT1R) gene with BRS and BRSf in man. We found significant association of A1166C polymorphism in AT1 receptor gene with baroreflex sensitivity. Less frequent allele was associated with decreased BRS and BRSf.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů