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EN
ČeštinaEnglish

Whole genome sequencing of pathogenic and nonpathogenic treponemes: comparison of syphilis and yaws strains with T. paraluiscuniculi.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00029916" target="_blank" >RIV/00216224:14110/09:00029916 - isvavai.cz</a>

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    Whole genome sequencing of pathogenic and nonpathogenic treponemes: comparison of syphilis and yaws strains with T. paraluiscuniculi.

  • Original language description

    Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis, T. pallidum ssp. pertenue (TPE) causes endemic treponematosis yaws, and T. paraluiscuniculi is not infectious to humans but causes venereal spirochetosis in rabbits. The genomesof TPE strain Samoa D and T. paraluiscuniculi strain Cuniculi A were sequenced using several whole-genome sequencing methods. Obtained whole genome sequences were compared to the published sequence of TPA strain Nichols. The genome size of TPA Nichols (1,138,006 bp), TPE Samoa D (1,139,299 bp) and T. paraluiscuniculi Cuniculi A (1,133,391 bp) and the overall gene order is similar in all investigated genomes. More than 50% of Nichols and Samoa D genes encode sequentially identical proteins whereas only15% of those genes were found in the Cuniculi A and Samoa D genomes. Major sequence changes including frameshifts were found in 88 genes of the Cuniculi A genome when compared to the Nichols genome.

  • Czech name

    —

  • Czech description

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Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

    —

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Clinical Microbiology and Infection, Volume 15, Issue s4, Abstracts of the 19th ECCMID, P1329

  • ISBN

    —

  • ISSN

    1198-743X

  • e-ISSN

    —

  • Number of pages

    1

  • Pages from-to

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  • Publisher name

    European Society of Clinical Microbiology and Infectious Diseases

  • Place of publication

    Neuveden

  • Event location

    Helsinki

  • Event date

    May 16, 2009

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article

    —

Similar results(10)

Comparison ot the syphilis and yaws spirochete genomes: comparative genome sequencing of T. pallidum ssp. pallidum Samoa D.Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome DecayComparing genomes of pathogenic and non-pathogenic spirochetes: DNA-microarray hybridizations, whole genome fingerprinting and DNA sequencing.