Role of thiamine status and genetic variability in transketolase and other pentose phosphate cycle enzymes in the progression of diabetic nephropathy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00046873" target="_blank" >RIV/00216224:14110/10:00046873 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/11:#0000549
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Role of thiamine status and genetic variability in transketolase and other pentose phosphate cycle enzymes in the progression of diabetic nephropathy
Original language description
Pentose phosphate pathway (PPP) represents a potentially protective mechanism in hyperglycaemia due to shunting of glycolytic intermediates into PPP reactions. We hypothesized that thiamine status (plasma and erythrocyte levels of thiamine and its esters) together with genetic variability in key PPP enzymes transketolase (TKT), transaldolase and TKT-like might contribute to the progression of diabetic nephropathy (DN) and mortality of diabetics.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NR9443" target="_blank" >NR9443: Genetic variability of pentose phosphate pathway as a modulating factor of the onset and progression of diabetic nephropathy</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nephrol Dial Transplant
ISSN
1460-2385
e-ISSN
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Volume of the periodical
2010
Issue of the periodical within the volume
9
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
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UT code for WoS article
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EID of the result in the Scopus database
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